Dienogest Tablets

Dienogest Tablets are available with the branding “GESTPLUS” and are an androgen and progestogen hormonal preparation taken orally; thus it has an endocrine mechanism of action in that they inhibit the action of endothelin, a vasoconstrictor hormone. Thus it decreases endothelin and augments the blood vessels’ dilation hence decreasing the workload placed on the heart and lungs.

Dienogest Tablets are primarily ordered to manage Pulmonary Arterial Hypertension which is a situation whereby there is raised pressure of the blood in the lungs and this puts pressure on the heart. It is also prescribed in secondary Raynaud’s phenomenon, the frequency, and severity of attacks of Raynaud, to reduce. Endothelin receptors B are antagonised by Dienogest; this makes it easier for oxygen to be delivered to tissues in the body reducing other symptoms like breathlessness and fatigue.

Medical Benefits

• It can enhance the capability of exercising for a longer time without needing some rest.
• Helps to reduce shortness of breath and fatigue thus simplifying tasks that are accomplished.
• It enhances daily living by increasing mobility and producing a better quality of life.
• It helps to lower the risk of disease progression.
• It also replaces regular injections with an easily taken by mouth in pill form.

Directions For Use

• Consume the Dienogest Tablets as directed by your doctor.
• Take the tablet with water, without chewing or crushing it down into a fine powder.
• It is for oral use and may be administered with or without food.
• Adhere to the advice of your healthcare provider.

Storage

• Keep it in a cool and dry place, away from light, not in a refrigerator, or exposed to heat.
• Do not let children under 12 years of age have the product at their disposal.
• It is recommended to use within thirty days from the date that is printed on the foil of the packaging.

Precautions

• It may interact with Aminoglutethimide, Anticoagulants (e.g. warfarin), Anti-seizure medications (e.g., topiramate, carbamazepine), Corticosteroids (e.g., prednisone), HIV/AIDS medications (e.g., ritonavir), Antifungal medications (e.g., ketoconazole), antibiotics (e.g., rifampicin). Consult a doctor before taking this medicine.
• Inform your doctor before taking Dienogest Tablets about any existing medical conditions or allergies.
• Check with your doctor before using the product if you are pregnant or if you could become pregnant.
• Check for any complications, especially hepatic or renal.
• Caution should be used in people who have a history of blood clots or cardiovascular disease.
• Do not use alcohol as the use may worsen the side effects.

Side Effects

• Flushing
• Headache
• Fatigue
• Nasal congestion
• Respiratory tract infections

Frequently Asked Questions (FAQs)

Is there a generic version of this medicine? 

Currently, Dienogest is available by its brand name, and generics may be available depending on the region. Check with your pharmacist or doctor for options.

What makes this tablet different from other treatments for PAH? 

Dienogest targets endothelin receptors to relax blood vessels, improving blood flow and reducing symptoms like breathlessness and fatigue, offering a more specific treatment for PAH.

Can I take this composition if I have a history of heart disease?

If you have a heart condition, consult your doctor before using Dienogest, as it may affect blood circulation and heart function.

Will this medicine help in reducing the frequency of Raynaud’s phenomenon episodes?

Dienogest can sometimes reduce Raynaud’s episodes, but consult your doctor for personalized advice.

Is this medication effective for all types of PAH?

Dienogest is effective for treating PAH but may not work for all types. Your doctor will decide if it’s suitable for you.