Medroxyprogesterone Tablets

Ezitrone-10 contains Medroxyprogesterone Acetate (MPA), a synthetic progestin similar to the natural hormone progesterone. It regulates ovulation and menstrual periods and is used to treat a variety of menstrual disorders and hormone-related conditions in women.

Mechanism of Action:

Medroxyprogesterone works by modifying the endometrium (lining of the uterus), suppressing ovulation, and inhibiting gonadotropin production through negative feedback on the hypothalamus and pituitary.

Indications:

• Amenorrhea (absence of menstruation) – primary or secondary
• Dysfunctional uterine bleeding due to hormonal imbalance
• Endometriosis (as part of hormonal therapy)
• Menstrual irregularities
• Hormone Replacement Therapy (HRT) – in combination with estrogens to prevent endometrial hyperplasia
• Contraception (in higher doses or injectable form)

Benefits:

• Regulates menstrual cycle
• Prevents abnormal uterine bleeding
• Can be part of HRT for menopausal women
• Well-tolerated with predictable hormonal effects

Dosage & Administration:

• Typical dose: 10 mg once daily for 5 to 10 days, starting on Day 16–21 of the menstrual cycle, or as directed by a physician.
• Withdrawal bleeding typically occurs 3–7 days after stopping the medication.

Common Side Effects:

• Nausea
• Breast tenderness
• Headache
• Mood changes
• Weight changes
• Irregular spotting or bleeding

Storage Conditions:

• Store at room temperature
• Protect from moisture and direct sunlight
• Keep out of reach of children