Medroxyprogesterone Injection

Medroxyprogesterone Injection comes with the branding “EZI-TRONE” and belongs to a category of medicines called progestogens for long-term contraceptive hormonal treatment. Family planning contraception is a process conducted to avoid unwanted pregnancies that may be hazardous to the family’s health.

Medroxyprogesterone Injection contains medroxyprogesterone acetate which is slightly different to the natural hormone known as progesterone, which is secreted by the ovaries approximately halfway through your menstrual cycle.

When using this medicine, the maturation of an egg and its release from the ovaries is inhibited during your period. There is no possibility of pregnancy if there’s no release of egg so that sperm cannot fertilise the egg.

Medical Benefits

• This medicine contains medroxyprogesterone acetate (DMPA), a man-made progestin similar to the natural hormone, progesterone.
• It inhibits the growth and release of an egg from the ovaries during your menstrual cycle commonly referred to as ovulation.
• If it is not released then there is no chance the egg can be fertilized by sperm hence no pregnancy.
• It also changes the endometrial lining, making it harder for conception to occur.
• It causes changes in the cervical mucus making it difficult for sperm to penetrate and fertilise the egg.

Directions for Use

• Medroxyprogesterone Injection can be administered only through injections by a specialist.
• It is usually given at an interval of approximately three months, that is, every 12 weeks.
• Consult your doctor to determine when and how often should you receive the shots

Storage

• Keep the injection at room temperature away from heat and any source of moisture.
• Do not freeze this injection.
• It is advisable not to allow children to have access to this drug.

Precautions

• This injection is not advisable for patients who have an allergic reaction to any of the ingredients of the injection and inform the doctor about allergies.
• Before you take this medicine, tell your doctor if you have/ had migraines, irregular or heavy periods, blood clots (for example deep vein blood clots), diabetes, severe pain or swelling of the calf muscles, eye problems, depression, osteoporosis, asthma, epilepsy or any type of hormone dependant breast or sexual organ cancer.
• Consult your doctor if you are pregnant or breastfeeding, or if you plan to become pregnant.
• Medroxyprogesterone Injection may have an interaction with aminoglutethimide, blood thinners like warfarin and anti-seizure medications like topiramate.
• If you develop any of the following conditions, contact your doctor: Genital bleeding, low bone mass density, breast cancer, Liver disorders, Thromboembolism or blood clotting problems.

Side Effects

• Feeling sick
• Feeling bloated
• Hair loss
• Acne
• Rash
• Back pain

Frequently Asked Questions (FAQs)

In which cases is this composition not advisable?

Do not use if you are allergic to its ingredients, have/had breast cancer, blood clotting issues, severe liver disease, unexplained vaginal bleeding, or if you’re pregnant or haven’t started your periods.

Can I consume other oral contraceptives with this injection?

Do not take other contraceptives with Depo-Provera without your doctor’s advice.

Can this medicine cause hair loss?

Yes, it may cause hair loss. Consult your doctor if hair fall becomes severe.

Is this medication ideal for one or two-time use?

Yes, it is useful temporarily in cases like waiting for a partner’s vasectomy, rubella immunization, or before sterilization.

Is this medicine a contraceptive pill?

No, it’s an injectable contraceptive, not a pill.