Trosoft Injection contains Fosfomycin, a broad-spectrum bactericidal antibiotic effective against Gram-positive and Gram-negative bacteria, including multidrug-resistant (MDR) strains. It works by inhibiting bacterial cell wall synthesis at an early stage and is especially useful in urinary tract infections (UTIs) and complicated systemic infections.
Indications and Uses:
- Complicated urinary tract infections (cUTIs)
- Pyelonephritis
- Prostatitis caused by susceptible organisms
- Nosocomial infections including pneumonia, bacteremia, and sepsis
- Multidrug-resistant infections including those caused by ESBL, MRSA, and CRE (as per sensitivity)
Key Benefits:
- Rapid bactericidal activity
- Broad-spectrum coverage, including resistant strains
- Good tissue penetration
- Can be used in renal-compromised patients (dose-adjusted)
Common Side Effects:
- Local injection site reactions
- Diarrhea or mild gastrointestinal upset
- Headache or dizziness
- Rare: Hypokalemia or elevated liver enzymes (on long-term use)
Storage Instructions:
- Store below 25°C
- Protect from light and moisture
- Reconstitute only with appropriate sterile diluent before IV administration
- Use immediately after reconstitution or as per hospital guidelines