Defender-10 contains Ritodrine Hydrochloride 10 mg, a selective β2-adrenergic agonist used primarily as a tocolytic agent to manage premature labor. It helps delay preterm delivery, allowing more time for fetal maturation or corticosteroid administration.
Therapeutic Class:
Tocolytic / Uterine Relaxant
Indications:
- Management of threatened preterm labor
- Prevention of premature uterine contractions
- Delaying delivery to facilitate fetal lung maturity or maternal transfer
Mechanism of Action:
Ritodrine selectively stimulates beta-2 adrenergic receptors in uterine smooth muscle, causing relaxation of the uterus. This helps in inhibiting premature uterine contractions without significant cardiovascular effects at therapeutic doses.
Dosage & Administration:
- Defender-10 is generally administered 10 mg orally every 4 to 6 hours, or as directed by a physician.
- Dosage may be titrated based on uterine activity and maternal response.
- Should be used under close obstetric supervision.
Side Effects Common
- Tachycardia
- Nervousness
- Tremors
- Palpitations
- Nausea
- Headache
Storage:
Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.